Ontology highlight
ABSTRACT:
SUBMITTER: Shirako S
PROVIDER: S-EPMC6779755 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
NPJ science of food 20191007
PyroGlu-Leu is present in certain food protein hydrolysates and traditional Japanese fermented foods. Our previous study demonstrated that the oral administration of pyroGlu-Leu (0.1 mg/kg body weight) attenuates dysbiosis in mice with experimental colitis. The objective of this study was to elucidate why such a low dose of pyroGlu-Leu attenuates dysbiosis in different animal models. High fat diet extensively increased the ratio of <i>Firmicutes/Bacteroidetes</i> in feces of rats compared to con ...[more]