Ontology highlight
ABSTRACT:
SUBMITTER: Liao CH
PROVIDER: S-EPMC6780514 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Liao Chien-Huang CH Lai I-Chun IC Kuo Hui-Ching HC Chuang Shuang-En SE Lee Hsin-Lun HL Whang-Peng Jacqueline J Yao Chih-Jung CJ Lai Gi-Ming GM
Marine drugs 20190908 9
Malignant glioma (MG) is a poor prognostic brain tumor with inevitable recurrence after multimodality treatment. Searching for more effective treatment is urgently needed. Differentiation induction via epigenetic modification has been proposed as a potential anticancer strategy. Natural products are known as fruitful sources of epigenetic modifiers with wide safety margins. We thus explored the effects of oligo-fucoidan (OF) from brown seaweed on this notion in MG cells including Grade III U87MG ...[more]