Ontology highlight
ABSTRACT:
SUBMITTER: Majkowska-Pilip A
PROVIDER: S-EPMC6781293 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Majkowska-Pilip Agnieszka A Halik Paweł Krzysztof PK Gniazdowska Ewa E
Pharmaceutics 20190901 9
To date, our understanding of the Substance P (SP) and neurokinin 1 receptor (NK1R) system shows intricate relations between human physiology and disease occurrence or progression. Within the oncological field, overexpression of NK1R and this SP/NK1R system have been implicated in cancer cell progression and poor overall prognosis. This review focuses on providing an update on the current state of knowledge around the wide spectrum of NK1R ligands and applications of radioligands as radiopharmac ...[more]