Ontology highlight
ABSTRACT:
SUBMITTER: Bhutani S
PROVIDER: S-EPMC6783266 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Bhutani Surabhi S Howard James D JD Reynolds Rachel R Zee Phyllis C PC Gottfried Jay J Kahnt Thorsten T
eLife 20191008
Sleep deprivation has marked effects on food intake, shifting food choices toward energy-dense options. Here we test the hypothesis that neural processing in central olfactory circuits, in tandem with the endocannabinoid system (ECS), plays a key role in mediating this relationship. We combined a partial sleep-deprivation protocol, pattern-based olfactory neuroimaging, and <i>ad libitum</i> food intake to test how central olfactory mechanisms alter food intake after sleep deprivation. We found t ...[more]