Ontology highlight
ABSTRACT:
SUBMITTER: Rezhdo A
PROVIDER: S-EPMC6783319 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Rezhdo Arlinda A Islam Mariha M Huang Manjie M Van Deventer James A JA
Current opinion in biotechnology 20190408
There is growing evidence that noncanonical amino acids (ncAAs) can be utilized in the creation of biological therapeutics ranging from protein conjugates to cell-based therapies. However, when does genetically encoding ncAAs yield biologics with unique properties compared to other approaches? In this review, we attempt to answer this question in the broader context of therapeutic development, emphasizing advances within the past two years. In several areas, ncAAs add valuable routes to therapeu ...[more]