Ontology highlight
ABSTRACT:
SUBMITTER: Celik SBG
PROVIDER: S-EPMC6784416 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Celik Sevde B G SBG Dominici Sébastien R SR Filby Benjamin W BW Das Anupam A K AAK Madden Leigh A LA Paunov Vesselin N VN
Biomimetics (Basel, Switzerland) 20190711 3
Most current methods for the preparation of tissue spheroids require complex materials, involve tedious physical steps and are generally not scalable. We report a novel alternative, which is both inexpensive and up-scalable, to produce large quantities of viable human keratinocyte cell clusters (clusteroids). The method is based on a two-phase aqueous system of incompatible polymers forming a stable water-in-water (w/w) emulsion, which enabled us to rapidly fabricate cell clusteroids from HaCaT ...[more]