Ontology highlight
ABSTRACT:
SUBMITTER: Ferreira I
PROVIDER: S-EPMC6784847 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Ferreira Izabela I Jolley Elizabeth A EA Znosko Brent M BM Weber Gerald G
Chemical physics 20190117
We calculate the nearest-neighbour enthalpies and entropies at 5 salt concentrations of 18 RNA sequences, each for at least 9 different species concentrations, totalling 757 melting temperatures, using a melting temperature optimization method. These new parameters do not need to be salt-corrected and are shown to provide overall improved melting temperature predictions. They show a marked quadratic dependence with salt concentrations which are compensated to form linear Gibbs free energies. Two ...[more]