Ontology highlight
ABSTRACT:
SUBMITTER: Angelbello AJ
PROVIDER: S-EPMC6785366 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Angelbello Alicia J AJ Chen Jonathan L JL Disney Matthew D MD
Annals of the New York Academy of Sciences 20190409 1
Aberrant RNA structure and function operate in neurological disease progression and severity. As RNA contributes to disease pathology in a complex fashion, that is, via various mechanisms, it has become an attractive therapeutic target for small molecules and oligonucleotides. In this review, we discuss the identification of RNA structures that cause or contribute to neurological diseases as well as recent progress toward the development of small molecules that target them, including small molec ...[more]