Ontology highlight
ABSTRACT:
SUBMITTER: Maurer S
PROVIDER: S-EPMC6785788 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Maurer Sabine S Herhaus Peter P Lippenmeyer Romina R Hänscheid Heribert H Kircher Malte M Schirbel Andreas A Maurer H Carlo HC Buck Andreas K AK Wester Hans-Jürgen HJ Einsele Hermann H Grigoleit Götz-Ulrich GU Keller Ulrich U Lapa Constantin C
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20190308 10
The chemokine receptor CXC-chemokine receptor 4 (CXCR4) is a transmembrane receptor involved in survival, proliferation, and dissemination of different cancers, including hematopoietic malignancies. Relapsed or refractory hematopoietic cancers are frequently resistant to conventional therapy, and novel highly active strategies are urgently needed. CXCR4-directed endoradiotherapy constitutes a highly promising targeted therapeutic concept. Here, we investigated the adverse effects of this novel t ...[more]