Dataset Information

Genome Sequences of Barmah Forest Virus Strains Isolated from Mosquitoes Trapped in Australian Defence Force Training Areas Reveal Multiple Nucleotide Insertions in the 3' Untranslated Region.

ABSTRACT: The complete genome sequences of two Barmah Forest virus (BFV) strains isolated from mosquitoes trapped in the Australian Defence Force (ADF) training areas during 2017 and 2018 reveal multiple nucleotide insertions in the 3' untranslated region (UTR) of ADF BFV strains compared with the BFV prototype strain whole-genome sequence in GenBank.

SUBMITTER: Liu W

PROVIDER: S-EPMC6787324 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature

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Genome Sequences of Barmah Forest Virus Strains Isolated from Mosquitoes Trapped in Australian Defence Force Training Areas Reveal Multiple Nucleotide Insertions in the 3' Untranslated Region.

Liu Wenjun W Kizu Joanne R JR Hoare Christina C Mitchell Ian R IR Gauci Penelope J PJ Gubala Aneta J AJ

Microbiology resource announcements 20191010 41

The complete genome sequences of two Barmah Forest virus (BFV) strains isolated from mosquitoes trapped in the Australian Defence Force (ADF) training areas during 2017 and 2018 reveal multiple nucleotide insertions in the 3' untranslated region (UTR) of ADF BFV strains compared with the BFV prototype strain whole-genome sequence in GenBank. ...[more]

PMID: 31601667

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Project description:AIMS:Understanding the time-course of post-traumatic stress disorder (PTSD), and the underlying events, may help to identify those most at risk, and anticipate the number of individuals likely to be diagnosed after exposure to traumatic events. METHOD:Data from two health surveys were combined to create a cohort of 1119 Australian military personnel who deployed to the Middle East between 2000 and 2009. Changes in PTSD Checklist Civilian Version (PCL-C) scores and the reporting of stressful events between the two self-reported surveys were assessed. Logistic regression was used to examine the association between the number of stressful events reported and PTSD symptoms, and assess whether those who reported new stressful events between the two surveys, were also more likely to report older events. We also assessed, using linear regression, whether higher scores on the Kessler Psychological Distress Scale or the Alcohol Use Disorder Identification Test were associated with subsequent increases in the PCL-C in those who had experienced a stressful event, but who initially had few PTSD symptoms. RESULTS:Overall, the mean PCL-C scores in the two surveys were similar, and 78% of responders stayed in the same PCL-C category. Only a small percentage moved from having few symptoms of PTSD (PCL-C < 30) in Survey 1 to meeting the criteria for PTSD (PCL-C ? 50) at Survey 2 (1% of all responders, 16% of those with PCL-C ? 50 at Survey 2). Personnel who reported more stressful lifetime events were more likely to score higher on the PCL-C. Only 51% reported the same stressful event on both surveys. People who reported events occurring between the two surveys were more likely to record events from before the first survey which they had not previously mentioned (OR 1.48, 95% CI (1.17, 1.88), p < 0.001), than those who did not. In people who initially had few PTSD symptoms, a higher level of psychological distress, was significantly associated with higher PCL-C scores a few years later. CONCLUSIONS:The reporting of stressful events varied over time indicating that while the impact of some stressors endure, others may increase or decline in importance. When screening for PTSD, it is important to consider both traumatic experiences on deployment and other stressful life events, as well as other mental health problems among military personnel, even if individuals do not exhibit symptoms of PTSD on an initial assessment.

Dataset Information

Genome Sequences of Barmah Forest Virus Strains Isolated from Mosquitoes Trapped in Australian Defence Force Training Areas Reveal Multiple Nucleotide Insertions in the 3' Untranslated Region.

Publications

Genome Sequences of Barmah Forest Virus Strains Isolated from Mosquitoes Trapped in Australian Defence Force Training Areas Reveal Multiple Nucleotide Insertions in the 3' Untranslated Region.

Similar Datasets

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