Ontology highlight
ABSTRACT:
SUBMITTER: Zhao Y
PROVIDER: S-EPMC6788963 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Zhao Yimu Y Rafatian Naimeh N Wang Erika Y EY Feric Nicole T NT Lai Benjamin F L BFL Knee-Walden Ericka J EJ Backx Peter H PH Radisic Milica M
Matrix biology : journal of the International Society for Matrix Biology 20190411
Organ-on-a-chip systems have the potential to revolutionize drug screening and disease modeling through the use of human stem cell-derived cardiomyocytes. The predictive power of these tissue models critically depends on the functional assembly and maturation of human cells that are used as building blocks for organ-on-a-chip systems. To resemble a more adult-like phenotype on these heart-on-a-chip systems, the surrounding micro-environment of individual cardiomyocyte needs to be controlled. Her ...[more]