Ontology highlight
ABSTRACT:
SUBMITTER: Wilmschen S
PROVIDER: S-EPMC6789710 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Wilmschen Sarah S Schmitz Joern E JE Kimpel Janine J
Vaccines 20190919 3
Extensive research on generating an efficient HIV vaccine is ongoing. A major aim of HIV vaccines is the induction of long-lasting, broadly neutralizing antibodies (bnAbs) that can confer sterile immunity for a prolonged period of time. Several strategies have been explored to reach this goal, i.e. protein immunization, DNA, or viral vectors, or a combination thereof. In this review, we give an overview of approaches using viral vectors for the induction of HIV-specific bnAbs. Many pre-clinical ...[more]