Ontology highlight
ABSTRACT:
SUBMITTER: Nakhjavani M
PROVIDER: S-EPMC6789838 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Nakhjavani Maryam M Palethorpe Helen M HM Tomita Yoko Y Smith Eric E Price Timothy J TJ Yool Andrea J AJ Pei Jinxin V JV Townsend Amanda R AR Hardingham Jennifer E JE
Pharmaceuticals (Basel, Switzerland) 20190801 3
Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies have been reported on the anti-cancer effects of the different epimers. The aim was to investigate the stereoselective effects of the Rg3 epimers on triple negative breast cancer (TNBC) cell lines, tested using cell-based assays for proliferation, apoptosis, cell cycle arrest, migration and invasion. Molecular doc ...[more]