Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez-Lopez R
PROVIDER: S-EPMC6790057 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Hernández-López Rubí R Lorincz Attila T AT Torres-Ibarra Leticia L Reuter Caroline C Scibior-Bentkowska Dorota D Warman Rhian R Nedjai Belinda B Mendiola-Pastrana Indira I León-Maldonado Leith L Rivera-Paredez Berenice B Ramírez-Palacios Paula P Lazcano-Ponce Eduardo E Cuzick Jack J Salmerón Jorge J
Clinical epigenetics 20191012 1
<h4>Background</h4>Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance of S5 (targeting DNA methylation in HPV16, HPV18, HPV31, HPV33, and human gene EPB41L3) to predict cervical intraepithelial neoplasia grade 2 or higher (CIN2+) in a sample of hrHPV-infected women referred to colposcopy in the FRIDA Study, a large screening trial in Mexico. A nested case-control sample with women referred ...[more]