Ontology highlight
ABSTRACT:
SUBMITTER: Hernandez-Lopez R
PROVIDER: S-EPMC6790057 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Clinical epigenetics 20191012 1
<h4>Background</h4>Vigilant management of women with high-risk human papillomavirus (hrHPV) is necessary in cancer screening programs. To this end, we evaluated the performance of S5 (targeting DNA methylation in HPV16, HPV18, HPV31, HPV33, and human gene EPB41L3) to predict cervical intraepithelial neoplasia grade 2 or higher (CIN2+) in a sample of hrHPV-infected women referred to colposcopy in the FRIDA Study, a large screening trial in Mexico. A nested case-control sample with women referred ...[more]