Altered learning under uncertainty in unmedicated mood and anxiety disorders.
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ABSTRACT:
SUBMITTER: Aylward J
PROVIDER: S-EPMC6790140 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
Altered learning under uncertainty in unmedicated mood and anxiety disorders.
Aylward Jessica J Valton Vincent V Ahn Woo-Young WY Bond Rebecca L RL Dayan Peter P Roiser Jonathan P JP Robinson Oliver J OJ
Nature human behaviour 20190617 10
Anxiety is characterized by altered responses under uncertain conditions, but the precise mechanism by which uncertainty changes the behaviour of anxious individuals is unclear. Here we probe the computational basis of learning under uncertainty in healthy individuals and individuals suffering from a mix of mood and anxiety disorders. Participants were asked to choose between four competing slot machines with fluctuating reward and punishment outcomes during safety and stress. We predicted that ...[more]
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