Ontology highlight
ABSTRACT:
SUBMITTER: Lepe JA
PROVIDER: S-EPMC6790883 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Lepe J A JA Rodríguez-Villodres A A Martín-Gutiérrez G G Luque R R Aznar J J
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20190912 5
<h4>Objective</h4>To evaluate if the in vitro activity of ampicillin increases when combined with ceftriaxone.<h4>Methods</h4>The activity of ampicillin and ceftriaxone was evaluated against six Listeria monocytogenes invasive clinical isolates. Ampicillin and ceftriaxone MICs were determined by the broth microdilution method. Synergy was evaluated by checkerboard and time-kill curves methods.<h4>Results</h4>All six L. monocytogenes strains were susceptible to ampicillin (MICs 0.25-0.5 mg/L). A ...[more]