Ontology highlight
ABSTRACT:
SUBMITTER: Jabbari E
PROVIDER: S-EPMC6790973 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Jabbari Edwin E Woodside John J Tan Manuela M X MMX Pavese Nicola N Bandmann Oliver O Ghosh Boyd C P BCP Massey Luke A LA Capps Erica E Warner Tom T TT Lees Andrew J AJ Revesz Tamas T Holton Janice L JL Williams Nigel M NM Grosset Donald G DG Morris Huw R HR
Movement disorders : official journal of the Movement Disorder Society 20190712 9
<h4>Background</h4>Studies on early-onset presentations of progressive supranuclear palsy (PSP) have been limited to those where a rare monogenic cause has been identified. Here, we have defined early-onset PSP (EOPSP) and investigated its genetic and clinico-pathological profile in comparison with late-onset PSP (LOPSP) and Parkinson's disease (PD).<h4>Methods</h4>We included subjects from the Queen Square Brain Bank, PROSPECT-UK study, and Tracking Parkinson's study. Group comparisons of data ...[more]