Ontology highlight
ABSTRACT:
SUBMITTER: Climer LK
PROVIDER: S-EPMC6794386 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Climer Leslie K LK Cox Andrew M AM Reynolds Timothy J TJ Simmons Dwayne D DD
Frontiers in molecular neuroscience 20191009
EF-hand Ca<sup>2+</sup>-binding protein family members, α- and β-parvalbumins have been studied for decades. Yet, considerable information is lacking distinguishing functional differences between mammalian α-parvalbumin (PVALB) and oncomodulin (OCM), a branded β-parvalbumin. Herein, we provide an overview detailing the current body of work centered around OCM as an EF-Hand Ca<sup>2+</sup>-binding protein and describe potential mechanisms of OCM function within the inner ear and immune cells. Add ...[more]