Ontology highlight
ABSTRACT:
SUBMITTER: Poole E
PROVIDER: S-EPMC6795026 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Poole Emma E Huang Christopher J Z CJZ Forbester Jessica J Shnayder Miri M Nachshon Aharon A Kweider Baraa B Basaj Anna A Smith Daniel D Jackson Sarah Elizabeth SE Liu Bin B Shih Joy J Kiskin Fedir N FN Roche K K Murphy E E Wills Mark R MR Morrell Nicholas W NW Dougan Gordon G Stern-Ginossar Noam N Rana Amer A AA Sinclair John J
Frontiers in microbiology 20191009
Herpesviruses undergo life-long latent infection which can be life-threatening in the immunocompromised. Models of latency and reactivation of human cytomegalovirus (HCMV) include primary myeloid cells, cells known to be important for HCMV latent carriage and reactivation <i>in vivo</i>. However, primary cells are limited in availability, and difficult to culture and to genetically modify; all of which have hampered our ability to fully understand virus/host interactions of this persistent human ...[more]