Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor.
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ABSTRACT:
SUBMITTER: Shi X
PROVIDER: S-EPMC6796948 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Cas9 has no exonuclease activity resulting in staggered cleavage with overhangs and predictable di- and tri-nucleotide CRISPR insertions without template donor.
Shi Xin X Shou Jia J Mehryar Mohammadreza M MM Li Jingwei J Wang Leyang L Zhang Mo M Huang Haiyan H Sun Xiaofang X Wu Qiang Q
Cell discovery 20191001
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