Ontology highlight
ABSTRACT:
SUBMITTER: Cabello-Olmo M
PROVIDER: S-EPMC6801436 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Cabello-Olmo Miriam M Araña Miriam M Radichev Ilian I Smith Paul P Huarte Eduardo E Barajas Miguel M
International journal of molecular sciences 20190926 19
Type 1 diabetes mellitus (T1D) is an autoimmune illness that affects millions of patients worldwide. The main characteristic of this disease is the destruction of pancreatic insulin-producing beta cells that occurs due to the aberrant activation of different immune effector cells. Currently, T1D is treated by lifelong administration of novel versions of insulin that have been developed recently; however, new approaches that could address the underlying mechanisms responsible for beta cell destru ...[more]