Ontology highlight
ABSTRACT:
SUBMITTER: Wu BT
PROVIDER: S-EPMC6807418 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Wu Bor-Tsang BT Lin Wei-Yong WY Chou I-Ching IC Liu Hsin-Ping HP Lee Cheng-Chun CC Tsai Yuhsin Y Wu Wan-Chen WC Tsai Fuu-Jen FJ
Journal of clinical laboratory analysis 20130701 4
<h4>Background</h4>Genetic, environmental, immunological, and hormonal factors contribute to the etiology of Tourette syndrome (TS). From the genetic standpoint, TS is a heterogeneous disorder. In our previous study, we found that a single nucleotide polymorphism (SNP) of x-ray repair cross-complementing group 1 (XRCC1), a DNA repair gene, was associated with TS. Previous studies also showed that tyrosyl-DNA phosphodiesterase 1 (TDP1) interacts with XRCC1 to repair damaged DNA. However, the rela ...[more]