Ontology highlight
ABSTRACT:
SUBMITTER: Motoda H
PROVIDER: S-EPMC6812228 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Motoda Hirotoshio H Hiragami Fukumi F Kawamura Kenji K Inoue Shigeki S Gomita Yutaka Y Kano Yoshio Y
Heliyon 20191015 10
We investigated the differentiation and activation of p38 MAPK induced by contrast bath in drug-hypersensitive PC12m3 mutant cells. The rate of neurite outgrowth in PC12m3 cells induced by contrast bath was much higher than that induced by warming or cooling alone or that induced by two warmings with an interval of room temperature, indicating that contrast bath has a synergistic effect. The results of an experiment using a p38 MAPK inhibitor, SB203580, showed that neurite outgrowth of PC12m3 ce ...[more]