Assessment of acute bone loading in humans using [18F]NaF PET/MRI.
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ABSTRACT:
SUBMITTER: Haddock B
PROVIDER: S-EPMC6813760 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
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Assessment of acute bone loading in humans using [<sup>18</sup>F]NaF PET/MRI.
Haddock Bryan B Fan Audrey P AP Uhlrich Scott D SD Jørgensen Niklas R NR Suetta Charlotte C Gold Garry Evan GE Kogan Feliks F
European journal of nuclear medicine and molecular imaging 20190805 12
<h4>Purpose</h4>The acute effect of loading on bone tissue and physiology can offer important information with regard to joint function in diseases such as osteoarthritis. Imaging studies using [<sup>18</sup>F]-sodium fluoride ([<sup>18</sup>F]NaF) have found changes in tracer kinetics in animals after subjecting bones to strain, indicating an acute physiological response. The aim of this study is to measure acute changes in NaF uptake in human bone due to exercise-induced loading.<h4>Methods</h ...[more]
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