Ontology highlight
ABSTRACT:
SUBMITTER: Collin G
PROVIDER: S-EPMC6813871 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Collin Guusje G Seidman Larry J LJ Keshavan Matcheri S MS Stone William S WS Qi Zhenghan Z Zhang Tianhong T Tang Yingying Y Li Huijun H Anteraper Sheeba Arnold SA Niznikiewicz Margaret A MA McCarley Robert W RW Shenton Martha E ME Wang Jijun J Whitfield-Gabrieli Susan S
Molecular psychiatry 20181108 10
The emergence of prodromal symptoms of schizophrenia and their evolution into overt psychosis may stem from an aberrant functional reorganization of the brain during adolescence. To examine whether abnormalities in connectome organization precede psychosis onset, we performed a functional connectome analysis in a large cohort of medication-naive youth at risk for psychosis from the Shanghai At Risk for Psychosis (SHARP) study. The SHARP program is a longitudinal study of adolescents and young ad ...[more]