Ontology highlight
ABSTRACT:
SUBMITTER: Walker MJ
PROVIDER: S-EPMC6814141 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Walker Matthew J MJ Varani Gabriele G
Methods in enzymology 20190613
RNA structures play a pivotal role in many biological processes and the progression of human disease, making them an attractive target for therapeutic development. Often RNA structures operate through the formation of complexes with RNA-binding proteins, however, much like protein-protein interactions, RNA-protein interactions span large surface areas and often lack traditional druggable properties, making it challenging to target them with small molecules. Peptides provide much greater surface ...[more]