Ontology highlight
ABSTRACT:
SUBMITTER: Yeoh JW
PROVIDER: S-EPMC6816779 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Yeoh Jing Wui JW Corrias Alberto A Buist Martin L ML
Cellular and molecular bioengineering 20170206 2
The colon is a digestive organ that is subject to a wide range of motility disorders. However, our understanding of the etiology of these disorders is far from complete. In this study, a quantitative single cell model has been developed to describe the electrical behaviour of a human colonic smooth muscle cell (hCSMC). This model includes the pertinent ionic channels and intracellular calcium homoeostasis. These components are believed to contribute significantly to the electrical response of th ...[more]