Ontology highlight
ABSTRACT:
SUBMITTER: Hu H
PROVIDER: S-EPMC6816959 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Hu Haochang H Chen Xiaoying X Zhou Cong C Li Bin B Yang Yong Y Ying Xiuru X Mao Yiyi Y Zhang Yihan Y Zhong Jie J Dai Jie J Yu Hang H Wu Boyi B Li Xiaodong X Wang Tiangong T Duan Shiwei S
Journal of clinical laboratory analysis 20171205 5
<h4>Background</h4>Non-small cell lung cancer (NSCLC) is a common malignant tumor. DNA hypermethylation in the promoter region has been served as a potential molecular marker for several tumors. The goal of the current study was to assess the diagnostic ability of mutL homolog 1 (MLH1) promoter methylation in NSCLC.<h4>Methods</h4>A total of 111 NSCLC patients' paired tissue samples were obtained to explore the association between MLH1 promoter methylation and NSCLC by methylation-specific polym ...[more]