Ontology highlight
ABSTRACT:
SUBMITTER: Shoeibi A
PROVIDER: S-EPMC6817677 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Shoeibi Ali A Olfati Nahid N Litvan Irene I
Frontiers in neurology 20191022
Progressive supranuclear palsy (PSP) is a four-repeat tau proteinopathy. Abnormal tau deposition is not unique for PSP and is the basic pathologic finding in some other neurodegenerative disorders such as Alzheimer's disease (AD), age-related tauopathy, frontotemporal degeneration, corticobasal degeneration, and chronic traumatic encephalopathy. While AD research has mostly been focused on amyloid beta pathology until recently, PSP as a prototype of a primary tauopathy with high clinical-patholo ...[more]