Dataset Information

Estimating National-Level Exposure to Antineoplastic Agents in the Workplace: CAREX Canada Findings and Future Research Needs.

ABSTRACT:

Objectives

Occupational exposure to antineoplastic agents occurs in various environments and is associated with increased cancer risk and adverse reproductive outcomes. National-level information describing the location and extent of occupational exposure to antineoplastic agents is unavailable in Canada and most other countries. CAREX Canada aimed to estimate the prevalence and relative levels of occupational exposures to antineoplastic agents across work setting, occupation, and sex.

Methods

'Exposure' was defined as any potential for worker contact with antineoplastic agents. Baseline numbers of licensed workers were obtained from their respective professional bodies. For unlicensed workers, Census data or data extrapolated from human resources reports (e.g., staffing ratios) were used. Prevalence was estimated by combining population estimates with exposure proportions from peer-reviewed and grey literature. Exposure levels (classified as low, moderate, and high) by occupation and work setting were estimated qualitatively by combining estimates of contact frequency and exposure control practices.

Results

Approximately 75000 Canadians (0.42% of the total workforce) are estimated as occupationally exposed to antineoplastic agents; over 75% are female. The largest occupational group exposed to antineoplastic agents is community pharmacy workers, with 30200 exposed. By work setting, 39000 workers (52% of all exposed) are located in non-hospital settings; the remaining 48% are exposed in hospitals. The majority (75%) of workers are in the moderate exposure category.

Conclusions

These estimates of the prevalence and location of occupational exposures to antineoplastic agents could be used to identify high-risk groups, estimate disease burden, and target new research and prevention activities. The limited secondary data available for developing these estimates highlights the need for increased quantitative measurement and documentation of antineoplastic agent contamination and exposure, particularly in work environments where use is emerging.

SUBMITTER: Hall AL

PROVIDER: S-EPMC6824530 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Publications

Estimating National-Level Exposure to Antineoplastic Agents in the Workplace: CAREX Canada Findings and Future Research Needs.

Hall Amy L AL Demers Paul A PA Astrakianakis George G Ge Calvin C Peters Cheryl E CE

Annals of work exposures and health 20170701 6

<h4>Objectives</h4>Occupational exposure to antineoplastic agents occurs in various environments and is associated with increased cancer risk and adverse reproductive outcomes. National-level information describing the location and extent of occupational exposure to antineoplastic agents is unavailable in Canada and most other countries. CAREX Canada aimed to estimate the prevalence and relative levels of occupational exposures to antineoplastic agents across work setting, occupation, and sex.<h ...[more]

PMID: 28595280

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Project description:BackgroundIn 2002–2003, a Needs, Gaps and Opportunities Assessment (NGOA) was conducted to investigate relationships between socio-economic dimensions of housing and health. Recent reviews of the literature point to a dearth of research on the socioeconomic dimensions of housing and health, despite its potential for promoting health.MethodsThe NGOA sought to identify research needs and gaps, and future opportunities for research in housing, socio-economic status and health. The methods used included a literature scan, a scan of research capacity, eight regional stakeholder workshops across Canada, and an open-ended e-mail survey of stakeholders. In this paper, we report the findings of the stakeholder consultations.FindingsThe main finding of the NGOA was that there is a significant dearth of research on housing as a socio-economic determinant of health but enormous potential for conducting high-impact, longitudinal and quasi-experimental research in the area. Of particular interest to stakeholder participants in the NGOA were the economic aspects of housing and health; the impact of housing on health for vulnerable subgroups (e.g., Aboriginal peoples, immigrants, children, seniors); the role of socio-economically and ethnically mixed communities; and the interaction between socio-economic aspects of housing and biophysical hazards in the home.ConclusionThe NGOA demonstrated that there is a substantial audience eager for knowledge on housing as a socio-economic determinant of health and that such knowledge could make an immediate impact on policy decision-making and program operation. Although knowledge gaps are substantial, the NGOA clearly identifies opportunities for high-impact, longitudinal and quasi-experimental research. Recently signed federal-provincial funding agreements for housing make the findings of the NGOA timely. Moreover, the NGOA results demonstrate how research on housing as a socio-economic determinant of health could be a strategy for improving our understanding of the effects of social environments on health and for reducing health disparities.Electronic Supplementary MaterialSupplementary material is available for this article at 10.1007/BF03405392 and is accessible for authorized users.

Dataset Information

Estimating National-Level Exposure to Antineoplastic Agents in the Workplace: CAREX Canada Findings and Future Research Needs.

Objectives

Methods

Results

Conclusions

Publications

Estimating National-Level Exposure to Antineoplastic Agents in the Workplace: CAREX Canada Findings and Future Research Needs.

Similar Datasets

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