Ontology highlight
ABSTRACT:
SUBMITTER: Diederichs T
PROVIDER: S-EPMC6828756 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Diederichs Tim T Pugh Genevieve G Dorey Adam A Xing Yongzheng Y Burns Jonathan R JR Hung Nguyen Quoc Q Tornow Marc M Tampé Robert R Howorka Stefan S
Nature communications 20191104 1
Nanopores are key in portable sequencing and research given their ability to transport elongated DNA or small bioactive molecules through narrow transmembrane channels. Transport of folded proteins could lead to similar scientific and technological benefits. Yet this has not been realised due to the shortage of wide and structurally defined natural pores. Here we report that a synthetic nanopore designed via DNA nanotechnology can accommodate folded proteins. Transport of fluorescent proteins th ...[more]