Ontology highlight
ABSTRACT:
SUBMITTER: Yang ZB
PROVIDER: S-EPMC6832660 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Yang Zai-Bo ZB Li Pei P He Yin-Ju YJ
Molecules (Basel, Switzerland) 20191019 20
As a continuation of our efforts to discover and develop "me-better" active molecules, in this study, a series of novel isoxazole-amide derivatives containing an acylhydrazone moiety were synthesized and evaluated for their antiviral activities against tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). Antiviral bioassays indicated that some of the target compounds exhibited better in vivo antiviral activities against TMV and CMV than those of Ningnanmycin (NNM). Especially, the compoun ...[more]