Ontology highlight
ABSTRACT:
SUBMITTER: Zhang H
PROVIDER: S-EPMC6834430 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Zhang Hongwei H Liao Zhibin Z Liu Furong F Su Chen C Zhu He H Li Yani Y Tao Ran R Liang Huifang H Zhang Bixiang B Zhang Xuewu X
Aging 20191023 20
Long noncoding RNAs (lncRNAs) are overexpressed in many types of cancers, suggesting they may promote tumorigenesis. The lncRNA "highly upregulated in liver cancer" (HULC) promotes hepatocellular carcinoma (HCC) by mechanisms that are not fully understood. In the present study, we showed that HULC is overexpressed in HCC tissues, which correlates with an unfavorable prognosis in HCC patients. We also found that HULC promotes the proliferation, migration, and invasion of HCC cells <i>in vitro</i> ...[more]