Ontology highlight
ABSTRACT:
SUBMITTER: Spindler MC
PROVIDER: S-EPMC6834585 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Spindler Marie-Christin MC Filbeck Sebastian S Stigloher Christian C Benavente Ricardo R
Scientific reports 20191106 1
The synaptonemal complex is a multiprotein complex, which mediates the synapsis and recombination between homologous chromosomes during meiosis. The complex is comprised of two lateral elements and a central element connected by perpendicular transverse filaments (TFs). A 3D model based on actual morphological data of the SC is missing. Here, we applied electron tomography (ET) and manual feature extraction to generate a quantitative 3D model of the murine SC. We quantified the length (90 nm) an ...[more]