Ontology highlight
ABSTRACT:
SUBMITTER: Heber S
PROVIDER: S-EPMC6836032 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Heber Stefan S Fischer Michael J M MJM
Medical sciences (Basel, Switzerland) 20190923 10
TRPA1, a versatile ion channel of the Transient Receptor Potential (TRP) channel family, detects a large variety of chemicals and can contribute to signal processing of other stimuli, e.g., due to its sensitivity to cytosolic calcium elevation or phosphoinositolphosphate modulation. At first, TRPA1 was found on sensory neurons, where it can act as a sensor for potential or actual tissue damage that ultimately may elicit pain or itch as warning symptoms. This review provides an update regarding t ...[more]