Ontology highlight
ABSTRACT:
SUBMITTER: Cai W
PROVIDER: S-EPMC6837841 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Cai Weibin W Tan Jing J Yan Jianyun J Zhang Lu L Cai Xiaoqiang X Wang Haiping H Liu Fang F Ye Maoqing M Cai Chen-Leng CL
Cell reports 20190701 1
The regeneration capacity of neonatal mouse heart is controversial. In addition, whether epicardial cells provide a progenitor pool for de novo heart regeneration is incompletely defined. Following apical resection of the neonatal mouse heart, we observed limited regeneration potential. Fate-mapping of Tbx18<sup>MerCreMer</sup> mice revealed that newly formed coronary vessels and a limited number of cardiomyocytes were derived from the T-box transcription factor 18 (Tbx18) lineage. However, furt ...[more]