Ontology highlight
ABSTRACT:
SUBMITTER: Bryant DM
PROVIDER: S-EPMC4302033 | biostudies-literature | 2015 Feb
REPOSITORIES: biostudies-literature
Bryant Donald Marion DM O'Meara Caitlin Claire CC Ho Nhi Ngoc NN Gannon Joseph J Cai Lei L Lee Richard Theodore RT
Journal of molecular and cellular cardiology 20141219
The finding that neonatal mice are able to regenerate myocardium after apical resection has recently been questioned. We determined if heart regeneration is influenced by the size of cardiac resection and whether surgical retraction of the ventricular apex results in an increase in cardiomyocyte cell cycle activity. We performed moderate or large apical ventricular resections on neonatal mice and quantified scar infiltration into the left ventricular wall at 21 days post-surgery. Moderately rese ...[more]