Ontology highlight
ABSTRACT:
SUBMITTER: Haas JT
PROVIDER: S-EPMC6837876 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Haas Joel T JT Vonghia Luisa L Mogilenko Denis A DA Verrijken An A Molendi-Coste Olivier O Fleury Sébastien S Deprince Audrey A Nikitin Artemii A Woitrain Eloïse E Ducrocq-Geoffroy Lucie L Pic Samuel S Derudas Bruno B Dehondt Hélène H Gheeraert Céline C Van Gaal Luc L Driessen Ann A Lefebvre Philippe P Staels Bart B Francque Sven S Dombrowicz David D
Nature metabolism 20190614 6
Progression of fatty liver to non-alcoholic steatohepatitis (NASH) is a rapidly growing health problem. Presence of inflammatory infiltrates in the liver and hepatocyte damage distinguish NASH from simple steatosis. However, the underlying molecular mechanisms involved in the development of NASH remain to be fully understood. Here we perform transcriptional and immune profiling of NASH patients before and after lifestyle intervention (LSI). Analysis of liver microarray data from a cohort of pati ...[more]