Ontology highlight
ABSTRACT:
SUBMITTER: Cherpokova D
PROVIDER: S-EPMC6839959 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Cherpokova Deya D Jouvene Charlotte C CC Libreros Stephania S DeRoo Elise P EP Chu Long L de la Rosa Xavier X Norris Paul C PC Wagner Denisa D DD Serhan Charles N CN
Blood 20191001 17
Deep vein thrombosis (DVT) is a common cardiovascular disease with a major effect on quality of life, and safe and effective therapeutic measures to efficiently reduce existent thrombus burden are scarce. Using a comprehensive targeted liquid chromatography-tandem mass spectrometry-based metabololipidomics approach, we established temporal clusters of endogenously biosynthesized specialized proresolving mediators (SPMs) and proinflammatory and prothrombotic lipid mediators during DVT progression ...[more]