Ontology highlight
ABSTRACT:
SUBMITTER: Sun K
PROVIDER: S-EPMC6841704 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Nature communications 20191108 1
Nanoscale transport through nanopores and live-cell membranes plays a vital role in both key biological processes as well as biosensing and DNA sequencing. Active translocation of DNA through these nanopores usually needs enzyme assistance. Here we present a nanopore derived from truncated helicase E1 of bovine papillomavirus (BPV) with a lumen diameter of c.a. 1.3 nm. Cryogenic electron microscopy (cryo-EM) imaging and single channel recording confirm its insertion into planar lipid bilayer (BL ...[more]