Ontology highlight
ABSTRACT:
SUBMITTER: Stiso J
PROVIDER: S-EPMC6849479 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Cell reports 20190901 10
Optimizing direct electrical stimulation for the treatment of neurological disease remains difficult due to an incomplete understanding of its physical propagation through brain tissue. Here, we use network control theory to predict how stimulation spreads through white matter to influence spatially distributed dynamics. We test the theory's predictions using a unique dataset comprising diffusion weighted imaging and electrocorticography in epilepsy patients undergoing grid stimulation. We find ...[more]