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Confidence bands for multiplicative hazards models: Flexible resampling approaches.


ABSTRACT: We propose new resampling-based approaches to construct asymptotically valid time-simultaneous confidence bands for cumulative hazard functions in multistate Cox models. In particular, we exemplify the methodology in detail for the simple Cox model with time-dependent covariates, where the data may be subject to independent right-censoring or left-truncation. We use simulations to investigate their finite sample behavior. Finally, the methods are utilized to analyze two empirical examples with survival and competing risks data.

SUBMITTER: Dobler D 

PROVIDER: S-EPMC6849815 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature

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Confidence bands for multiplicative hazards models: Flexible resampling approaches.

Dobler Dennis D   Pauly Markus M   Scheike ThomasH T  

Biometrics 20190417 3


We propose new resampling-based approaches to construct asymptotically valid time-simultaneous confidence bands for cumulative hazard functions in multistate Cox models. In particular, we exemplify the methodology in detail for the simple Cox model with time-dependent covariates, where the data may be subject to independent right-censoring or left-truncation. We use simulations to investigate their finite sample behavior. Finally, the methods are utilized to analyze two empirical examples with s  ...[more]

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