Ontology highlight
ABSTRACT:
SUBMITTER: Zheng S
PROVIDER: S-EPMC6853035 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Zheng Shuyu S Zhao Tingting T Yuan Shuijuan S Yang Lingyu L Ding Jinmei J Cui Li L Xu Mingqing M
Frontiers in microbiology 20191101
The crosstalk between the gut microbiota and immune state of the host is an essential focus in academia and clinics. To explore the dynamic role of the microbiota in response to immune deficiency, we comprehensively assessed the microbiome of 90 mouse fecal samples, across three time points including two immunodeficiency models, namely severe combined immunodeficient (SCID) mice and non-obese diabetic SCID (NOD/SCID) mice, with BALB/cA as a control strain. Metagenomic analysis revealed a decreas ...[more]