Dataset Information

Associations of long-term exposure to PM1, PM2.5, NO2 with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations.

ABSTRACT: OBJECTIVES:To evaluate the associations between long-term exposure to particulate matter with an aerodynamic diameter ?1.0??m and ?2.5??m (PM1 and PM2.5), nitrogen dioxide (NO2) and type 2 diabetes prevalence and fasting blood glucose levels in Chinese rural populations. MATERIAL AND METHODS:A total of 39, 259 participants were enrolled in The Henan Rural Cohort study. Questionnaires and medical examination were conducted from July 2015 to September 2017 in rural areas of Henan province, China. Three-year average residential exposure levels of PM1, PM2.5, NO2 for each subject were estimated by a spatiotemporal model. Logistic regression and linear regression models were applied to estimate the associations between PM1, PM2.5, NO2 exposure and type 2 diabetes prevalence and fasting blood glucose levels. RESULTS:The mean 3-year residential exposure concentrations of PM1, PM2.5 and NO2 was 57.4??g/m3, 73.4??g/m3 and 39.9??g/m3, respectively. Higher exposure concentrations of PM1, PM2.5, NO2 by 1??g/m3 was positively related to a 4.0% (95%CIs: 1.026, 1.054), 6.8% (1.052, 1.084) and 5.0% (1.039, 1.061) increase in odds of type 2 diabetes in the final adjusted models. Besides, a 1??g/m3 increase of PM1, PM2.5 and NO2 was related to a 0.020?mmol/L (95%CIs: 0.014, 0.026), 0.036?mmol/L (95%CIs: 0.030, 0.042) and 0.030?mmol/L (95%CIs: 0.026, 0.034) mmol/L higher fasting blood glucose levels. CONCLUSIONS:Higher exposure concentrations of air pollutants were positively related to the increased odds of type 2 diabetes, as well as higher fasting blood glucose levels in Chinese rural populations.

SUBMITTER: Liu F

PROVIDER: S-EPMC6853163 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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Associations of long-term exposure to PM<sub>1</sub>, PM<sub>2.5</sub>, NO<sub>2</sub> with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations.

Liu Feifei F Guo Yuming Y Liu Yisi Y Chen Gongbo G Wang Yuxin Y Xue Xiaowei X Liu Suyang S Huo Wenqian W Mao Zhenxing Z Hou Yitan Y Lu Yuanan Y Wang Chongjian C Xiang Hao H Li Shanshan S

Environment international 20191022 Pt B

<h4>Objectives</h4>To evaluate the associations between long-term exposure to particulate matter with an aerodynamic diameter ≤1.0 μm and ≤2.5 μm (PM<sub>1</sub> and PM<sub>2.5</sub>), nitrogen dioxide (NO<sub>2</sub>) and type 2 diabetes prevalence and fasting blood glucose levels in Chinese rural populations.<h4>Material and methods</h4>A total of 39, 259 participants were enrolled in The Henan Rural Cohort study. Questionnaires and medical examination were conducted from July 2015 to Septembe ...[more]

PMID: 31654916

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Dataset Information

Associations of long-term exposure to PM1, PM2.5, NO2 with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations.

Publications

Associations of long-term exposure to PM<sub>1</sub>, PM<sub>2.5</sub>, NO<sub>2</sub> with type 2 diabetes mellitus prevalence and fasting blood glucose levels in Chinese rural populations.

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