Dataset Information

Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity.

ABSTRACT:

Background

Adiposity-related ventilatory constraints in older adults can potentially contribute to greater risk of exercise intolerance and mobility disability. This study investigated whether ventilatory limitation, measured by breathing reserve (BR) at peak exercise, is associated with body composition and physical function in older adults with obesity.

Methods

This study was a cross-sectional analysis of data from a community-based cohort (N = 177) of older men and women (65-79 years) with obesity (body mass index = 30-45 kg/m2). All participants underwent cardiopulmonary exercise testing on a treadmill, dual-energy X-ray absorptiometry for body composition, and physical function assessments. We examined relationships between BR and body composition and physical function using multiple linear regression and compared a subset with (BR ? 30%; BR-low; n = 56) and without (BR ? 45%; BR-high, n = 48) ventilatory limitation using unpaired Student's t test and analysis of covariance.

Results

BR was inversely related to total body mass, lean mass, fat mass, % body fat, and waist circumference (p < 0.05 for all). BR was positively related to 400 m walk time (p = .006) and inversely related to usual gait speed (p = .05) and VO2peak (p < .0001), indicative of worse physical function. BR-low had greater adiposity, but also greater lean mass, higher VO2peak, and faster 400 m walk time, compared to BR-high (p < .05, for all).

Conclusions

Older adults with obesity who also have ventilatory limitation have overall higher measures of adiposity, but do not have lower peak exercise capacity or physical function. Thus, ventilatory limitation does not appear to be a contributing factor to obesity-related decrements in exercise tolerance or mobility.

SUBMITTER: Opina MTD

PROVIDER: S-EPMC6853661 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Publications

Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity.

Opina Maria Theresa D MTD Brinkley Tina E TE Gordon Michelle M Lyles Mary F MF Nicklas Barbara J BJ

The journals of gerontology. Series A, Biological sciences and medical sciences 20191101 12

<h4>Background</h4>Adiposity-related ventilatory constraints in older adults can potentially contribute to greater risk of exercise intolerance and mobility disability. This study investigated whether ventilatory limitation, measured by breathing reserve (BR) at peak exercise, is associated with body composition and physical function in older adults with obesity.<h4>Methods</h4>This study was a cross-sectional analysis of data from a community-based cohort (N = 177) of older men and women (65-79 ...[more]

PMID: 30535050

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Project description:BackgroundLower muscle and higher fat mass are characteristics of older adults; their physical function is also characterized by slower gait speed and weaker strength. However, the association between specific body composition and physical function is unclear.MethodsWe examined the association between body composition and physical performance using combined cross-sectional data of 1,821 participants from 13 clinical studies at Wake Forest University that used a consistent battery of tests. All participants were ≥60 years old and had one of the following conditions: healthy, osteoarthritis, coronary artery disease, obesity, heart failure, at elevated risk for disability, renal transplantation candidates, heart failure with preserved ejection fraction, moderate self-reported disability, hypertension, diabetes, or coronary artery disease, at high risk for cardiovascular disease. Data at enrollment from each study using uniform tools including body mass index (BMI), dual energy x-ray absorptiometry, physical performance assessment using 4 m walk speed, five chair rise time, handgrip strength, short physical performance battery (17), and Pepper Assessment Tool for Disability were analyzed.ResultsIncreased BMI was associated with slower walk speed, lower short physical performance battery, and higher Pepper Assessment Tool for Disability score. Increased percentage of body fat was associated with slower walk speed, lower hand grip strength, lower short physical performance battery scores, and higher Pepper Assessment Tool for Disability scores. Percent appendicular lean mass was associated with faster walk speed, higher handgrip strength, higher short physical performance battery, and lower Pepper Assessment Tool for Disability score. There were no significant discrepancies in relationship between body composition and physical function by gender except gender and BMI on chair-rise time.ConclusionsHigher BMI and percent body fat were associated with poor physical function while percent appendicular lean mass was associated with better physical function. There was no significant discrepancy in the by gender.

Project description:BackgroundSarcopenia is associated with loss of muscle mass and an increased risk of physical disability in elderly people. However, the prevalence of sarcopenia has increased in obese elderly populations. The purpose of this study was to identify the clinical efficacy of elastic resistance exercise training (RET) in patients with sarcopenic obesity.MethodsThis study was conducted at the rehabilitation center of a university-based teaching hospital and was designed as a prospective and randomized controlled trial with an intention-to-treat analysis. A total of 46 women aged 67.3 (5.2) years were randomly assigned to an experimental group (EG) and control group (CG). The EG underwent elastic RET for 12 weeks, and the CG received no RET intervention. All outcome measures were assessed at the baseline and posttest, including body composition measured using dual-energy X-ray absorptiometry, muscle quality (MQ) defined as a ratio of muscular strength to muscle mass, and physical capacity assessed using functional mobility tests. One-way analysis of covariance and Pearson correlation were used to compare outcomes between the 2 groups and to identify the relationship between changes in body composition and physical outcomes, respectively. A chi-square test was performed to identify differences in qualitative data between the 2 groups.ResultsAt the posttest, a significant between-group difference was observed in fat-free mass, MQ, and physical capacity (all P?<?.05); and a significant correlation was found between leg-lean-mass change and gait speed (r?=?0.36; P?<?.05). After 12 weeks of elastic RET intervention, the EG had significantly fewer patients exhibiting sarcopenia (P?<?.05) and experiencing physical difficulty (P?<?.001) than the CG.ConclusionThe present data suggest that elastic resistance exercise exerted benefits on the body composition, MQ, and physical function in patients with sarcopenic obesity. Regular exercise incorporating elastic RET should be used to attenuate muscle mass loss and prevent physical difficulty in obese older adults with sarcopenia on reconditioning therapy.Trial registrationChinese Clinical Trial Registry, ChiCTR-IPR-15006069.

Dataset Information

Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity.

Background

Methods

Results

Conclusions

Publications

Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity.

Similar Datasets

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