Ontology highlight
ABSTRACT:
SUBMITTER: Dong Y
PROVIDER: S-EPMC6857669 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Dong Yi Y Zhang XuePeng X Chen Jiajing J Zou Wenxing W Lin Songwen S Xu Heng H
Chemical science 20190812 38
The limitations of arene C-H functionalization of aryl sulfonamides containing strongly coordinating N-heterocycles were overcome using a Rh(iii) catalyst. The site-selectivity of C-H carbenoid functionalization at the <i>ortho</i> position relative to either the sulfonamide or N-heterocycle directing groups was elegantly switched using solvents of different polarities and different additive concentrations. Importantly, sulfonamide-group-directed <i>ortho</i>-C-H carbenoid functionalization tole ...[more]