Ontology highlight
ABSTRACT:
SUBMITTER: Kang B
PROVIDER: S-EPMC6859131 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Kang Bobin B Kim Chae Young CY Hwang Jisu J Sun Sojung S Yang Hyunwon H Suh Hyung Joo HJ Choi Hyeon-Son HS
Food science and biotechnology 20190427 6
This study was aimed to investigate the effect of red ginseng extract (RGE) on monocyte to macrophage differentiation and inflammatory signalings in THP-1 human monocytes. In HPLC analysis, RGE contained saponin level of 516 μg/mg (extract) with 14 ginsenosides. RGE effectively suppressed the monocyte-to-macrophage differentiation induced by phorbol 12-myristate 13-acetated (PMA) by inhibiting the THP-1 cell adhesion. This result is evidenced by the down-regulation of cluster of differentiation ...[more]