Ontology highlight
ABSTRACT:
SUBMITTER: Huddleston JP
PROVIDER: S-EPMC6859792 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Huddleston Jamison P JP Raushel Frank M FM
Biochemistry 20190829 37
The capsular polysaccharide (CPS) structure of <i>Campylobacter jejuni</i> contributes to its robust fitness. Many strains contain heptose moieties in their CPS units. The precursor heptose is GDP-d-<i>glycero</i>-α-d-<i>manno</i>-heptose; modifications to the stereochemistry at C3-C6 as well as additions of methyl and phosphoramidate groups lend to the hypervariability of the <i>C. jejuni</i> CPS structures. Synthesis of GDP-d-<i>glycero</i>-α-d-<i>manno</i>-heptose has been described previousl ...[more]