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Multifunctional Mineral Hydrogels: Potential in Artificially Intelligent Skins and Drug Delivery.

ABSTRACT: Hydrogels have received considerable attention due to their potential applications in the fields of drug delivery, tissue engineering, and stimuli-responsive devices. Nonetheless, it is still a great difficulty in designing hydrogels with multifunctional characteristics including excellent antibacterial activity and appropriate mechanical and remarkable sensing properties. In the present study, a novel type of organic-inorganic adhesive is demonstrated, which comprises inorganic matter of amorphous calcium phosphate particles and organic substances of poly(acrylic acid) and chitosan. The hydrogel possesses excellent biocompatible and antibacterial activity, unique viscoelastic properties, high quantity of drug load, and remarkably sensitive pressure sensing, which have potential use as antibacterial biomaterials, artificially intelligent skins, and drug delivery carriers.

SUBMITTER: Yan J

PROVIDER: S-EPMC6868877 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature

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Multifunctional Mineral Hydrogels: Potential in Artificially Intelligent Skins and Drug Delivery.

Yan Jufen J Zhu Jianhua J Cui Mingfang M Zhang Jing J Ma Fang F Su Yiping Y Han Xinya X

ACS omega 20191106 21

Hydrogels have received considerable attention due to their potential applications in the fields of drug delivery, tissue engineering, and stimuli-responsive devices. Nonetheless, it is still a great difficulty in designing hydrogels with multifunctional characteristics including excellent antibacterial activity and appropriate mechanical and remarkable sensing properties. In the present study, a novel type of organic-inorganic adhesive is demonstrated, which comprises inorganic matter of amorph ...[more]

PMID: 31763537

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