Ontology highlight
ABSTRACT:
SUBMITTER: Xue C
PROVIDER: S-EPMC6874126 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Xue Chang C Liu Xiaohui X Wen Bin B Yang Ruimeng R Gao Shuo S Tao Jiong J Zhou Jun J
Frontiers in cell and developmental biology 20191112
A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the regulatory hierarchies to ensure proper cardiogenesis in vertebrate. Major interaction proteins of the transcription cofactor vestigial like family member 4 (VGLL4) include myocyte enhancer factor 2 (MEF2) and TEA domain transcription factors (TEAD), both of which play important roles in embryonic cardiac development and in adulthood. In this study, we identified that t ...[more]